Showing posts with label inflammation. Show all posts
Showing posts with label inflammation. Show all posts

Sunday, January 29, 2012

Aspirin for teen acne


Understanding the causes of acne helps those that suffer from it have a better understanding of treating symptoms, and getting acne cleared faster and more efficiently. Acne is a common skin condition encountered by the adolescents and it affects both the sexes equally. The highest incidence is noted between the ages 14 and 17 for girls, and 16 and 19 for boys. It becomes more marked at puberty and during adolescence. Acne ia a follicular disorder affecting pilosebaceous follicles of the face, neck and upper trunk. They can present as whiteheads, blackheads, papules, pustules, nodules or cysts.

Acne appears to stem from an interplay of genetic, hormonal and bacterial factors. Each type is managed differently with different therapies. There is actually no predictable cure for the disease, but a combination of therapies will control the activity effectively. The basic treatment starts with skin hygiene, followed by dietary therapy, topical pharmacotherapy, systemic therapy and surgical treatment finally.

Aspirin, also called as acetylsalicylic acid is used as a topical treatment for acne. Aspirin is a non-steroidal anti-inflammatory drug and is used for treating many other problems as well. Aspirins are not used widely these days because of the difference in opinions about the effects and side effects of the drug. However, some doctors do prescribe aspirin for a few days because they are just applied topically over the skin lesions. The side effects like redness (erythema) and skin peeling should be immediately notified to the treating physician and the drug must be stopped on the first notice.

Aspirins act rapidly over the acne by reducing the inflammation at the site of application. They depress the sebum production and lead to the breakdown of the comedone plugs. The anti-inflammatory action suppresses the action of the organism causing inflammation. Initially there is some amount of redness and scaling noticed, soon the skin adjusts quickly to its use. Aspirin is available as over the counter and by prescription depending upon the combination and dosage used.

Instead of creams and gels, the aspirin tablets can be powdered and applied as face mask or used as a face wash. A few aspirin tablets should be powdered finely and made in the form of paste with water, then they are applied over the face, neck, upper back/chest (wherever required) as mask. They can be kept for 10-15 minutes and be washed with warm water. They have to be removed immediately if severe irritation or itching occurs. This can be applied once a week.

For face wash, a few aspirin tablets can be powdered coarsely and mixed with required amount of water (like a scrub) to wash the face. The face wash can be used once or twice a day daily. Again the adverse effects should be watched carefully. They are not advised for more than 12 weeks. It is better to consult your dermatologist before going for any such self treatments involving chemicals.

Most acne that arises during teenage are because of hormones and it resolves by its own without any treatment. But if it causes any problems like pain, pus discharge or scarring, its better to seek advice of the dermatologist and be treated accordingly. Washing the face daily (at least thrice) with plain warm water or mild cleansing soap will clear most of the acne.

Asthma

Asthma is a reversible obstructive airway disease that affects 17% of the American population. Although asthma can be fatal, more often it is just disruptive and affects day to day activities. Asthma can begin at any age, but in most cases it develops in childhood. Children usually develop allergic asthma which they outgrow by adolescence.

The common symptoms of asthma are cough, dyspnea and wheezing. These symptoms are manifested because of the narrowing of the airways. The symptoms and treatment of asthma depend upon the degree of airway narrowing. Asthma attacks frequently occur at night. The cause is not completely understood, but may be related to circardian variations, which influence the airway receptor thresholds. An asthmatic attack usually starts suddenly with coughing and a tight sensation in the chest. These symptoms are followed by slow, laborious, wheezy breathing. Generally expiration is always much more strenuous and prolonged than inspiration. This makes the asthmatics to sit upright and use every accessory muscle of respiration.

Obstructed air flow causes dyspnea. The cough at first is dry but soon it becomes forceful. Sputum, consisting of thin mucus containing small, round, gelatinous masses is coughed up with much difficulty. Later signs may include cyanosis (bluish discoloration) secondary to severe hypoxia, and symptoms of carbon dioxide retention, including sweating, tachycardia, and a widened pulse pressure. The symptoms of asthma may last from 30 minutes to several hours.

Other possible reactions that may accompany asthma include eczema, rashes, and temporary edema. The symptoms may occur periodically after exposure to a specific allergen, some medications, physical exertion, and emotional excitement.

Asthma symptoms can be reversed either spontaneously or by medical therapy. They can be effectively treated or controlled by medication therapy. There are five categories of medications that are used to treat asthma namely beta agonists, methylxanthines, anticholinergics, corticosteroids and mast cell inhibitors.

Beta Agonists:
Beta agonists are the initial medications used in the treatment of asthma because they dilate bronchial smooth muscles. They can also increase the ciliary movements and decrease the chemical mediators of anaphylaxis. The most commonly used beta adrenergic agents are epinephrine, albuterol, isoproterenol, metaproterenol and terbutaline. These medications are administered parenterally or by inhalation. Inhalation route is the best route of choice because it directly acts on the bronchioles and has only a few side effects.

Methylxanthines:
Methylxanthines, like aminophylline and theophylline are used in the treatment of asthme because of their bronchodilating effects. They relax the bronchial smooth muscles, increase movement of mucus in the airways and increase the contraction of diaphragm. Aminophylline is the IV form of theophylline and is administered intravenously. Theophylline is given orally.

Methylxanthines are not used in acute attacks because they are slow acting compared to beta agonists. There are several factors like tobacco smoking, heart failure, chronic liver disease, oral contraceptives, erythromycin and cimetidine which interfere with the metabolism of methylxanthines, particularly theophylline. Physician should be notified if any of the above mentioned condition exists before taking theophylline. Aminophylline should be administered very slowly, because giving them rapidly may cause tachycardia or cardiac dysrhythmias.

Anticholinergics:
Anticholinergic like atropine is not used in the routine treatment of asthma because of their systemic side effects such as dryness of the mouth, urinary hesitancy, blurred vision, palpitation and flushing. Atropine methylnitrate and ipratropium bromide have shown excellent bronchodilator effects with minimal side effects.They are administered by inhalation. Anticholinergics are particularly beneficial to asthmatics who are not candidates for beta agonists and methylxanthines because of underlying cardiac disease.

Corticosteroids: Corticosteroids are widely used in the treatment of asthma. These medicines can be administered intravenously (hydrocortisone), orally (prednisone), or by inhalation (dexamethasone, beclomethasone). The mechanism of action is not clear but they are thought to reduce inflammation and bronchoconstriction. Prolonged use of corticosteroids can result in serious side effects like peptic ulcers, osteoporosis, adrenal suppression, steroid myopathy and cataracts.

Inhaled corticosteroids are effective in the treatment of asthmatics with steroid dependent asthma. The advantage of this method of administration is the reduced side effects on other body systems. Throat irritation, coughing, dry mouth, hoarseness, and fungal infection of the mouth and pharynx may occur. Rinsing and gargling the mouth immediately after using inhaled corticosteroids will decrease the incidence of fungal infection. Any redness or presence of white patches in the mouth should be reported.

Mast cell inhibitors: Cromolyn sodium, a mast cell inhibitor is an integral part of the treatment of asthma. It is administered by inhalation. It prevents the release of chemical mediators of anaphylaxis, thereby resulting in bronchodilation and a decrease in airway inflammation. Cromolyn sodium is the most beneficial between attacks or while the asthma is in remission. It may result in the reduction of use of other medications and overall improvement in symptoms.

Status asthmaticus (severe and persistent asthma) is a medical emergency. The treatment is usually on an emergency room setting, and the person will be treated initially with beta agonists and corticosteroids. Oxygen therapy may be initiated for those who have dyspnea, cyanosis and hypoxemia.

These are the symptoms and treatment available for asthma. Identifying the early symptom and taking appropriate action will prevent emergencies.